Postoperative nausea and vomiting. ???? ? ??????? ??? ?? ??? (Postoperative nausea and vomiting)
Conditions
Interventions
Intervention 1: Intervention group 1: Like the control group, will receive 5 mL/kg of ringer lactate serum as compensatory intravascular volume expansion (CVE) and maintenance serum during surgery (40
with the difference that intervention group 1 will receive 500 mL of D5 solution (containing 25 g of glucose) in addition to the same serums described above. The total serum will be injected from the
with the difference that intervention group 2 will receive 500 mL of D10 solution (containing 50g of glucose) in addition to the same serums described above. The total serum will be injected from the
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Female patients aged 18 to 65 undergoing rhinoplasty Patients who are candidates for rhinoplasty surgery Patients in ASA ? and ASA ? class
Exclusion criteria
Exclusion criteria: History of diabetes mellitus (DM) Known congestive heart failure (CHF) Pregnant women Recent opioid use (within 48 hours before surgery) Having a history of postoperative nausea and vomiting (PONV) or motion sickness Smoker patients Known renal or hepatic failure or impaired preoperative tests Patients who have used anti-nausea medication 24 hours before surgery. Patients who have abnormal blood sugar on the morning of surgery. (Blood sugar more than 125 mg/dL) Known sensitivity to anesthetics used in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the effect of different doses of intravenous dextrose solution administered intraoperatively on incidence and severity of postoperative nausea and vomiting. Timepoint: The incidence and severity of postoperative nausea and vomiting, based on the Visual analog nausea score, will be measured and recorded by nurses immediately, 30 minutes, 60 minutes, 90 minutes, 3 hours, 6 hours, 12 hours and 24 hours after entering the ward. In case of discharge in less than 24 hours, during a phone call, the patient's nausea and vomiting will be recorded, as well as the amount of anti-nausea medication (in the amount of 4 mg of intravenous and oral ondansetron during hospitalization or after discharge in case of vomiting). The duration of recovery will be recorded in all three groups. Also, blood sugar will be checked and recorded immediately, 30 minutes, 60 minutes, 90 minutes, 3 hours, 6 hours, 12 hours and 24 hours after the operation (if there is no glucose intolerance and the patients are discharged , blood sugar measurement will be stopped). An increase in blood sugar to more than 200 mg/dL will require intervention. The intervention method is the injection of 1 unit of short-acting insulin (like regular insulin) for every 25 mg/dL increase in blood sugar greater than 200 mg/dL. Method of measurement: Incidence and severity of nausea and vomiting (PONV), based on Visual analog nausea score criteria, immediately, 30 minutes, 60 minutes, 90 minutes, 3 hours, 6 hours, 12 hours and 24 hours after entering the ward, need for anti-inflammatory drugs Nausea (the amount consumed after 24 hours) of the patients and the duration of hospitalization are recorded according to a questionnaire that will be designed by the researcher. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Mofid Nakhaei
Rasht University of Medical Sciences
Outcome results
None listed