pregnant women. Eclampsia
Conditions
Interventions
Intervention 1: High dose group: 44 pregnant women will receive folic acid 5 mg daily from early pregnancy until delivery. Intervention 2: Low dose group: 44 pregnant women will receive folic acid 0.5
Prevention
High dose group: 44 pregnant women will receive folic acid 5 mg daily from early pregnancy until delivery.
Low dose group: 44 pregnant women will receive folic acid 0.5 mg daily from early pregnancy until delivery.
Sponsors
Drug Applied Research Center, Tabriz University of Medical Sciences- Tabriz- iran
Eligibility
Sex/Gender
Female
Age
20 Years to 30 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Pregnant women with mean of 30-20 years Exclusion Criteria: Hstory of heart disease; chronic hypertension;diabetes mellitus;renal disease; collagen tissue disease; history of preterm labor; abortion; taking calcium and ferrous sulfate; liver disease
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Osteoprotegerin. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: ELISA Kit.;RANKL. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: ELISA Kit.;TNFa. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: ELISA Kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Calcium. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: auto analyzer& Compared with control.;Phosphorus. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: auto analyzer& Compared with control.;Alkaline phosphatase. Timepoint: Before intervention and 36th week of pregnancy. Method of measurement: auto analyzer& Compared with control. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.nadereh rashtchizadeh
Drug Applied Research Center, Tabriz University of Medical Sciences
Outcome results
None listed