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hyperprolactinemia

Comparative study of the effect of marticaria chamomilla syrup and cabergoline on hyperprolactinemia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013122215891N1
Enrollment
158
Registered
2014-06-20
Start date
2014-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperprolactinaemia. Hyperprolactinaemia

Interventions

Intervention 1: Medication administration ( marticaria chamomilla syrup) 5 cc two times a day for 4 weeks. Intervention 2: Cabergoline 0.25 mg twice a week.
Treatment - Drugs
Medication administration ( marticaria chamomilla syrup) 5 cc two times a day for 4 weeks.

Sponsors

Dr. Minaei; Vice chancellor for research Traditional Medicine Faculty of Tehran University of Medica
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patient satisfaction; Female; Outpatients older than 18 years; Patient with asymptomatic or mild symptoms idiopathic hyperprolactinemia (menstrual disorders that are just starting with or without galactorrhea or without bothering galactorrhea alone); Serum prolactin level above 25 µgr/L Exclusion criteria: Patients older than 45 years; Patient with liver failure; Patient with kidney failure; Patient with hypothyroidism; Taking medication such as haloperidol, phenothiazine, butyrophenone, monoamine oxidase inhibitor, fluoxetine, sulpiride, metoclopramide, domperidone, tricyclic antidepressants, opioid, estrogen, verapamil, reserpine, methyldopa, benzodiazepine, cimetidine, medroxolol drugs and any medication that is effective in prolactin secretion in the last three months; The use of warfarin; The use of sedating; Prolactinoma( micro or macro adenoma); Adrenal, pituitary and hypothalamus disease; Pregnant women; Women who plan to become pregnant; Breast feeding; Autoimmune disease such as lupus; Long- term menstural disorders; Bothering galactorrhea; Underlying disease such as diabetes, hypertension and cancer; History of hyperprolactinemia treatment in the last 6 months; The use of propranolol and vasoconstrictor drugs; Raynaud’s disease; History sensitivity to ergot derivatives; History of stomach ulcers and gastrointestinal bleeding; Asthma; History of hay fever and allergic reaction to member of the compositae family such as yarrow, feverfew, artemisia, tansy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Serum prolactin level. Timepoint: Before and after the intervention. Method of measurement: Laboratory measurement.

Secondary

MeasureTime frame
Side effects. Timepoint: During the treatment. Method of measurement: questionnaire and Physical exam.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarya Kabiri

Traditional Medicine Faculty, Tehran University of Medical Sciences

m-kabiri@razi.tums.ac.ir, marya_kabiri@yahoo.om009821:55601274

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026