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The study of Livergol® effect on rheumatoid arthritis patients

The study of Livergol® effect on serum levels of tumor necrosis factor- a, malondialdehyde, interleukin-1,paraoxonase-1, catalase and neopterin in rheumatoid arthritis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013121915870N1
Enrollment
50
Registered
2015-05-23
Start date
2014-09-07
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatoid arthritis. Seropositive rheumatoid arthritis

Interventions

daily 3 tablets of 140 mg livergol® for 3 months.
Treatment - Drugs
daily 3 tablets of 140 mg livergol® for 3 months

Sponsors

Vice Chancellor for research of Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: having four of the seven criteria, of American College of Rheumatology for six weeks and Diagnosis by a Rheumatologist Exclusion criteria: Patients participating in the study will be free to withdraw from the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Interleukin 1. Timepoint: before and after advising the drug. Method of measurement: ELISA.;TNF-a. Timepoint: before and after advising the drug. Method of measurement: ELISA.;Neopterin. Timepoint: before and after advising the drug. Method of measurement: HPLC.;Malondialdehyde. Timepoint: before and after advising the drug. Method of measurement: HPLC.;Catalase. Timepoint: before and after advising the drug. Method of measurement: spectrophotometry system.;Paraoxonase. Timepoint: before and after advising the drug. Method of measurement: spectrophotometry system.

Secondary

MeasureTime frame
ESR. Timepoint: before and after the drug. Method of measurement: westregreen.;CRP. Timepoint: before and after the drug. Method of measurement: ELISA.;Mmp-2. Timepoint: before and after the drug. Method of measurement: ELISA and gelatin zymography.;Mmp-9. Timepoint: before and after the drug. Method of measurement: ELISA and gelatin zymography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Amir Kiani

Kermanshah University of Medical Sciences

amir1kiani@yahoo.com+91 88316929

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026