multiple sclerosis. Multiple sclerosis
Conditions
Interventions
Intervention 1: Control group: placebo group (placebo) are used. Daily for six months with a number of food consumed. Dose: 250 Mlylygrm capsules containing starch. Intervention 2: Intervention group:
Treatment - Drugs
Control group: placebo group (placebo) are used. Daily for six months with a number of food consumed. Dose: 250 Mlylygrm capsules containing starch
Intervention group: a group of extract at a dose of 500 mg capsules to take. Daily for six months with a number of food
Intervention group: a group of extract at a dose of 250 mg capsules to take. Daily for six months with a number of food
Sponsors
Rafsanjan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria were an age of 16 to 55 years; a diagnosis of multiple sclerosis, according to the revised McDonald criteria; a relapsing–remitting course; one or more documented relapses in the previous year or two or more in the previous 2 years; and a score of 0 to 5.5 on the EDSS. exclusion criteria were relapse or corticosteroid treatment within 30 days before randomization, active infection, or clinically significant systemic disease.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disability. Timepoint: Before the experiment, three months after the intervention, and six months after intervention. Method of measurement: Expanded Disability Status Scale.;Relapse rate. Timepoint: Course of treatment. Method of measurement: number of confirmed relapses per year. | — |
Secondary
| Measure | Time frame |
|---|---|
| Different aspects of cognitive abilities. Timepoint: Before the experiment, three months and six months after the intervention. Method of measurement: Mini-Mental Status Examination tese.;Functional disability and cognitive. Timepoint: Before the experiment and six months after the intervention. Method of measurement: MULTIPLE SCLEROSIS FUNCTIONAL COMPOSITE test.;Learn Paired of words. Timepoint: Before the experiment, three months and six months after the intervention. Method of measurement: Paired words test.;Abstract reasoning and cognitive ability to adapt to environmental challenges. Timepoint: Before the experiment, three months and six months after the intervention. Method of measurement: Wisconsin card sorting test.;Anxiety. Timepoint: Before the experiment, three months and six months after the intervention. Method of measurement: Spielberger state-trait anxiety inventory.;Fatigue. Timepoint: Before the experiment, three months and six months after the intervention. Method of measurement: Fatigue Severity Scale test.;Depression. Timepoint: Before the experiment, three months and six months after the intervention. Method of measurement: Beck Depression Inventory.;Spasticity. Timepoint: Before the experiment, three months and six months after the intervention. Method of measurement: Ashworth test.;Number of gadolinium-enhancing lesions. Timepoint: Before the experiment and six months after the intervention. Method of measurement: MRI.;New lesion. Timepoint: Before the experiment and six months after the intervention. Method of measurement: MRI.;Resolvent. Timepoint: Before the experiment, three months and six months after the intervention. Method of measurement: TOWER OF LONDON TEST. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactfatemeh Ayoobi
Rafsanjan University of Medical Sciences
Outcome results
None listed