osteopenia of prematurity. Disorder of mineral metabolism, unspecified
Conditions
Interventions
Intervention 1: Administration of intravenous caffein with loading dose of 20 mg/kg and then 5-10 mg/kg from second day of birth till 34 week postmenstrual age to control group. Intervention 2: Adm
Treatment - Drugs
Administration of intravenous caffein with loading dose of 20 mg/kg and then 5-10 mg/kg from second day of birth till 34 week postmenstrual age to control group
Administration of intravenous aminophylin with loading dose of 3-5 mg/kg and then 1-2 mg/kg from second day of birth till 34 week post menstrual age to intervention group
Sponsors
Vice Chancellor for Research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: gestation age less than 32 weeks;aminophylin or caffeine recieption;osteopenia of prematurity survey on 45 days. Exclusion criteria: gestation age over 32 weeks; neonatal neuromuscular disorder; cholestasis; phenobarbital or corticosteroid therapy; birth asphyxia (apgar score less than 4 at 5 minute).
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Osteopenia of prematurity. Timepoint: 4 to 6 weeks after bith. Method of measurement: caLcium, phosphorus and alkalin phospatase measurment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Bronchopulmonary dysplasia. Timepoint: 28 days after birth and 36 weeks corrected gestation age. Method of measurement: The received FiO2. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Manizheh Mostafa Gharehbaghi
Tabriz University of Medical Sciences
Outcome results
None listed