Fatty liver disease. Diseases of liver
Conditions
Interventions
Intervention 1: Intervention 1: A capsule containing 500 mg of Cichorium intybus root extract is given to the patients group in the morning before breakfast. Intervention 2: Intervention 2: Two capsul
Treatment - Drugs
Intervention 1: A capsule containing 500 mg of Cichorium intybus root extract is given to the patients group in the morning before breakfast.
Intervention 2: Two capsules containing corn starch are given to the control group.
Sponsors
School of Traditional Medicine, Traditional Medicine and Materia Medica Research Center Shahid Behes
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion / Exclusion : Inclusion Criteria: Patient age of 18 to 70 years; fatty liver disease grade 1, 2 or 3 diagnosed by ultrasound; No current use of another drug for fatty liver treatment which has not been taken before. Exclusion Criteria :Advanced cardiovascular diseases, pulmonary or renal diseases; Pregnancy; Breast feeding; Allergy to Cichorium intybus; Non-compliance with medication; Psychiatric diseases complicating the results evaluation or causing patient’s lack of cooperation; Advanced cirrhosis; Hepatitis and other liver diseases except non-alcoholic fatty liver; alcohol consumption by patients; Fatty acid oxidation disorder ( congenital ); Patients with diabetes who are treated with insulin.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alanine Aminotransferase. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Aaspartat Aminotransferase. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer.;Fasting blood sugar. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer.;Total Cholesterol. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer.;Triglycerides. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer.;High-density lipoprotein. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer.;Low-density lipoprotein. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer.;Platelets. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer.;Albumin. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer.;Glucose tolerance test. Timepoint: Before intervention and two months after intervention. Method of measurement: Spectrophotometer.;Body Mass Index. Timepoint: Before intervention and two months after intervention. Method of measurement: Scale and Meter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Nikkhajooei
School of Traditional Medicine, Traditional Medicine and Materia Medica Research Center Shahid Behes
Outcome results
None listed