Human Pulp Regeneration. Dental drugs, topically applied
Conditions
Interventions
Intervention 1: intervention: ProRoot MTA/Treated Dentin Matrix in two separate layers of each 1mm thickness, pulpal layer includes TDM and then a layer of MTA covering it, for 6 weeks. Intervention 2
Treatment - Drugs
intervention: ProRoot MTA/Treated Dentin Matrix in two separate layers of each 1mm thickness, pulpal layer includes TDM and then a layer of MTA covering it, for 6 weeks.
control: ProRoot MTA
that covering the pulpal exposure in one layer of 2mm thickness
Sponsors
self-sponsored by researchers in study
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: patients between 18 to 30 years old; patients that have at least 3 mature and intact third molars to be extracted; healthy periodontal condition exclusion criteria: systemic diseases; medication intake
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical signs and symptoms (sensitivity to cold test and percussion). Timepoint: 1,3,7,14,21,28,35 and42 days after partial pulpotomy. Method of measurement: pulp vitality tests including thermal tests,Electric pulp test,pain, percussion, palpation,radiography.;Histologic pulp tissue evaluation including inflamation. Timepoint: day 42 after intervention. Method of measurement: light microscopic evaluation.;Histologic pulp tissue evaluation including dentin bridge formation. Timepoint: day 42 after intervention. Method of measurement: light microscopic evaluation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Histologic pulp tissue evaluation including pulp necrosis or abcess formation. Timepoint: after extraction(daye 42). Method of measurement: light microscopic evaluation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSohrab Tour Savadkouhi
Tehran Medical science Branch, Islamic Azad University
Outcome results
None listed