Evaluating the effect of vitamin E fortified whey drink on nutritional status, inflammatory markers and oxidative stress in hemodialysis patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201312132480N4

Enrollment

Registered

2013-12-28

Start date

2013-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodialysis. Extracorporeal dialysis

Interventions

Intervention 1: Consumption of 230 milliliters of whey drink three times a week. Intervention 2: Consumption of 230 milliliters of whey drink fortified with 400 milligrams of vitamin E three times a w

Treatment - Other

Consumption of 230 milliliters of whey drink three times a week

Consumption of 230 milliliters of whey drink fortified with 400 milligrams of vitamin E three times a week

Control group: no intervention

Consumption of 400 milligrams of vitamin E three times a week

Eligibility

Sex/Gender

All

Age

17 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: mean age of 17-65 years old; having mild, moderate or severe malnutrition based on the SGA (subjective global assessment) assessment; be dialyzed at least 2 times a week for 3 months. Exclusion criteria: hospitalization in the last month; active infection; using immunosuppressant drugs or multi-vitamins; pregnancy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Malnutrition. Timepoint: 2 months. Method of measurement: SGA assessment.;Malnutrition. Timepoint: 2 months. Method of measurement: SGA assessment.	—

Secondary

Measure	Time frame
Serum levels of malondialdehyde. Timepoint: 2 months. Method of measurement: TBA method (biochemical).;Serum levels of c-reactive protein. Timepoint: 2 months. Method of measurement: ELISA kit.;Serum transferrin. Timepoint: 2-months. Method of measurement: autoanalyzer.;Serum levels of albumin. Timepoint: 2-months. Method of measurement: autoanalyzer.;Serum lipoproteins. Timepoint: 2-months. Method of measurement: autoanalyzer.;Subjective Global Assessment. Timepoint: 2-months. Method of measurement: Questionnaire.;Quality of life. Timepoint: 2-months. Method of measurement: SF-12 questionnaire.;MIS. Timepoint: 2-months. Method of measurement: Questionnaire.;Weight. Timepoint: 2-months. Method of measurement: scale.	—

Measure

Time frame

Serum levels of malondialdehyde. Timepoint: 2 months. Method of measurement: TBA method (biochemical).;Serum levels of c-reactive protein. Timepoint: 2 months. Method of measurement: ELISA kit.;Serum transferrin. Timepoint: 2-months. Method of measurement: autoanalyzer.;Serum levels of albumin. Timepoint: 2-months. Method of measurement: autoanalyzer.;Serum lipoproteins. Timepoint: 2-months. Method of measurement: autoanalyzer.;Subjective Global Assessment. Timepoint: 2-months. Method of measurement: Questionnaire.;Quality of life. Timepoint: 2-months. Method of measurement: SF-12 questionnaire.;MIS. Timepoint: 2-months. Method of measurement: Questionnaire.;Weight. Timepoint: 2-months. Method of measurement: scale.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Sohrabi

Shiraz university of medical sciences

Zahra_2043@yahoo.com+98 917 711 3086

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026