Pain after lumbar disc surgery. Complications of medical and surgical care,Opioids and related analgesics
Conditions
Interventions
Intervention 1: Infusion of Naloxone 0.25mcg/kg/hr/IV in 500cc normal saline in 24 hours. Intervention 2: Infusion of Normal saline 500cc/IV in 24 hours.
Treatment - Drugs
Placebo
Infusion of Naloxone 0.25mcg/kg/hr/IV in 500cc normal saline in 24 hours
Infusion of Normal saline 500cc/IV in 24 hours
Sponsors
Vice chancellor for research, Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1) confirm the diagnosis with a physical examination and MRI 2) the willingness of patients to participate in the study and informed consent 3) non-emergency elective surgery discectomy 4) Age between 35-55 years Exclusion criteria: 1) patient reluctance every time that continued in the study, 2) a history of psychological illness, 3) a history of seizures, 4) abuse of alcohol or drugs 5) any unusual complications during surgery, 6) lack of neurologic injury
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity after surgery. Timepoint: 1, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analog Scale and Record in Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Amount of opioid consumption after surgery. Timepoint: 1, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analog Scale and Record in Questionnaire.;Pruritis after surgery. Timepoint: 1, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analog Scale and Record in Questionnaire.;Vomiting and nausea after surgery. Timepoint: 1, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analog Scale and Record in Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed