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The effect of magnesium supplementation on depression

The effect of oral magnesium supplementation on improvement of depression in depressed patients with magnesium deficiency

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013121015744N1
Enrollment
600
Registered
2014-08-15
Start date
2014-01-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. This block contains disorders in which the fundamental disturbance is a change in affect or mood to depression (with or without associated anxiety) or to elation. The mood change is usually accompanied by a change in the overall level of activity

Interventions

Intervention 1: The intervention group included 30 depressed patients with hypo magnesiumia will give daily two tablets of magnesium oxide. They will take tablets after breakfast and after dinner for
Treatment - Drugs
Placebo
The intervention group included 30 depressed patients with hypo magnesiumia will give daily two tablets of magnesium oxide. They will take tablets after breakfast and after dinner for 8 weeks. afte
The control group nclude of 30 depressed patients with hypo magnesium daily two tablets of placebo in terms of shape and color appearance similar to the magnesium tablet are a number after breakfast

Sponsors

Research Council (Research and Technology) of Shahid Sadooghi University of Medical Sciences and Hea
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: people aged 20-60 years old and depression is diagnosed by a psychiatrist; not suffering from disorders and diseases of the kidney, liver, heart, thyroid, bleeding disorders and malignancies; non- degenerative disease autoimmune; non- autoimmune degenerative diseases; lack of central nervous system diseases; no history of mental illness; lack of food; lack of consumption of antidepressants and diuretics during the last 3 months pregnant and not lactating and non- events include loss of job; divorce; death of first-degree relatives in the past 3 months and have not participated in other research projects that self -reporting of this information will be recorded. Exclusion criteria: people who are not more than 20 % of the drug; while studying people who start taking a multivitamin and mineral supplement may have changed who have created the drug are.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Depression. Timepoint: Before the intervention, and three months after intervention. Method of measurement: Beck Depression Inventory.;Serum magnesium. Timepoint: Three months after the intervention, but intervention. Method of measurement: Serum magnesium test.

Secondary

MeasureTime frame
Diarrhea. Timepoint: Monthly. Method of measurement: Ask the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactProf. Hassan Mozaffari Khosravi

Shahid Sadooghi University of Medical Sciences and Health Services in Yazd

mozaffari.kh@gmail.com+98 913 153 1467

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026