Post-traumatic stress disorder. Post-traumatic stress disorder
Conditions
Interventions
Intervention 1: Capsule D-cycloserine 25 mg twice daily for 4 weeks. Intervention 2: placebo twice daily for 4 weeks.
Treatment - Drugs
Placebo
Capsule D-cycloserine 25 mg twice daily for 4 weeks
placebo twice daily for 4 weeks
Sponsors
Isafahan Univaersity of Medical Sciences, Deputy of Research
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion: male; age over 18 and less than 65 years; being registered were registered with chronic combat-related PTSD in University affiliated psychiatric outpatient clinics in Isfahan;if already on psychopharmacologic treatments were required to be on a stable adequate drug regimen for the past three months. Exclusion: criteria of another DSM-IV-TR diagnosis; comorbid psychiatric condition including depression or substance abuse; a comorbid serious medical problem.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numbing and avoidance scores. Timepoint: 1st week, 5th, 7th, 11th weeks. Method of measurement: Clinician Administered PTSD Scale, Criterion C. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects. Timepoint: 1st, 5th, 7th,11th weeks. Method of measurement: Drug side effect questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Rajabi
IUMS, Behavioral Sciences Research Center
Outcome results
None listed