Skip to content

Effect of intravenous fluid sodium concentration on plasma sodium in pediatric patients

Comparison of the Effects of intravenous fluid with different concentrations of sodium on serum sodium levels in patients admitted to the intensive care unit of Bahrami Children's Hospital in 2012-13.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013121015740N1
Enrollment
100
Registered
2014-05-04
Start date
2012-12-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyponatremia. Hypo-osmolality and Hyponatremia

Interventions

Intervention 1: In the intervention group, in children over1 , the maintenance intravenous fluid with the common volume and calculated based on the Holliday-Segar formula containing 100 MEq of sodium
thus, for the first 10 kilograms, 100 cc weigh per kilogram of weight and for the second 10 kilogram, 50 cc per kilogram weight and for the rest of the weight, 20 cc per kilogram weight of the intrave
Treatment - Other
Treatment - Drugs
In the intervention group, in children over1 , the maintenance intravenous fluid with the common volume and calculated based on the Holliday-Segar formula containing 100 MEq of sodium per liter has be
In the control group, in children over 1 years old the maintenance intravenous fluid with the common volume and calculated through the Holliday-Segar formula containing 50 MEq of sodium per liter has

Sponsors

Vice chancellor for research, Tehran Univercity of Medcal Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: children in the age range 30 days to 14 years for his doctor prescribe intravenous fluid and pain for at least 24 hours in hospital pediatric intensive care Bahrami,Tehran University of Medical are admitted users. Exclusion criteria: patients with acute or chronic renal parenchymal problems, such as diabetic ketoacidosis and cerebral edema in patients at risk of trauma to the head, heart disease; hypoglycemic patients; patients with abnormal secretion of antidiuretic hormone; diabetes insipidus; pituitary or hypothalamic disorders. patients underwent surgery to have lost a lot of blood during surgery, and cranial thoracic surgery patients; cirrhotic patients; patients with severe malnutrition; diabetes, and his doctor to his patient fluid therapy in a framework designed this study can not reject. Withdrawal criteria; The research indicates that children with higher serum sodium lower than the normal range (135_145); the need to take CPR; being intubated; the death; early oral feeding; or any condition that a doctor's decision to withdraw his case if the study or decide to change intravenous fluids may be excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Plasma concentrations of sodium. Timepoint: 24 hours after initiation of intravenous fluid. Method of measurement: Sodium concentration in the blood sample.

Secondary

MeasureTime frame
Complications Haypvnatrmy. Timepoint: During and after reading. Method of measurement: Clinical interviews with hospital doctors.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Motahare Aghajani Delavar

Tehran Univercity of Medcal Sciences

maghajani@razi.tums.ac.ir; aghajani_14@yahoo.com+98 21 4441 2447

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026