Effect of dexamethasone and betamethasone on decreasing the complications after the surgical extraction of mandibular impacted third molars

Comparison between the effects of dexamethasone and betamethasone on decreasing the complications after the surgical extraction of mandibular impacted third molars

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201312093750N4

Enrollment

Registered

2014-01-20

Start date

2013-09-08

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mandibular impacted third molar.

Interventions

Intervention 1: Infiltrate injection of betamethasone (4 mg) corticosteroids at the buccal vestibule around the site of surgery. Intervention 2: Infiltrate injection of dexamethasone (8 mg) corticost

Treatment - Drugs

Infiltrate injection of betamethasone (4 mg) corticosteroids at the buccal vestibule around the site of surgery

Infiltrate injection of dexamethasone (8 mg) corticosteroids at the buccal vestibule around the site of surgery

Eligibility

Sex/Gender

All

Age

15 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age between 15 and 30 years; Pell and Gregory classification (class II or III); Equivalent degree of surgical difficulty comparing one side with the other. Exclusion criteria: Use of medication that could interfere with the healing process; Systemic disease; Pericoronitis ,infection or pain at the time of operation; Contraindications for using steroids; Recent history of non-steroidalanti inflammatory drug use; pregnant woman

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 2nd and 7th day after intervention. Method of measurement: Visual analogue scale.;Maximum mouth opening. Timepoint: Before and 2 and 7 days after the intervention. Method of measurement: Ruler.;Swelling. Timepoint: Before and 2 and 7 days after intervention. Method of measurement: Paper strip.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Bahman Derakhshan

International Campus, School Of Dentistry ,Tehran University of Medical Sciences

b-derakhshan@sina.tums.ac.ir+98 21 5585 1151

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026