stroke. Middle cerebral artery syndrome
Conditions
Interventions
Intervention 1: In case group we prescribed cap fluoxetin,20 mg, P.O. one time a day for 90 days. Intervention 2: In control group we prescribe a capsule with same size and color to fluoxetin ,(as pla
Treatment - Drugs
Placebo
In case group we prescribed cap fluoxetin,20 mg, P.O. one time a day for 90 days.
In control group we prescribe a capsule with same size and color to fluoxetin ,(as placebo) for 90 days.
Sponsors
Kermanshah University of Medical Science
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: inclusion criteria: stroke in middle cerebral artery( documented with imaging) and the patient have a hemi or mono plegy or paresis?the patient was not comatose ? filling the agreemnet sheet with patient or a reliable attendant ? the patient is dischargable and not admitted in ICU ward exclusion criteria: death of patient with any cause in duration of study ? irregular use of drugs ? irregular return for reexaminations ? presence of seizure, severe diarrhea, vomiting, severe insomnia ? presence of metabolic disorder( hyperthyroidism, hepatic , renal, cardiac,...) ? past medical history of psychiatric disorder or severe depression before stroke ? presence of SAH, lobar ICH, brain tumor ? stroke in other vascular territories (MCA, ACA,...) ? simmultaneous use of MAO-i , Selegiline, Cyproheptadine.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor deficit and psychiatric disorder. Timepoint: before study,day 45, day 90. Method of measurement: Hamilthon depression rating Scale(HDRS) for psychiatric disorders and Barthel Index( BI ) for motor assessment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactOmid Esmaeili M.D.
Kermanshah University of Medical Science
Outcome results
None listed