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The efficacy of an Iranian traditional medicinal drug in the treatment of cutaneous lesions of Pemphigus Vulgaris.

Comparison of therapeutic effect an Iranian traditional medicinal local drug and placebo in the treatment of cutaneous lesions of Pemphigus Vulgaris.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013120815720N1
Enrollment
20
Registered
2014-04-06
Start date
2013-12-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pemphigus vulgaris. Pemphigus vulgaris

Interventions

Intervention 1: applying local traditional medicinal gel drug to the lesion in intervention side twice daily in 30 days. Intervention 2: applying local placebo gel drug to the lesion in control side t
Treatment - Drugs
Placebo
applying local traditional medicinal gel drug to the lesion in intervention side twice daily in 30 days.
applying local placebo gel drug to the lesion in control side twice daily in 30 days.

Sponsors

Tehran University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients who has confirmed Pemphigus vulgaris in clinical manifestation and pathology and direct immunofluorescence; who has been admitted for the first time or in the relapse of disease; having two symmetrical lesions on the trunk or extremities; signing of informed consent. exclusion criteria: Pregnant or nursing patients; having drug sensitivity; face lesions; infected lesions.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Diameter of ?skin pemphigus lesions. Timepoint: 0, 15, 30. Method of measurement: ruler (mm).

Secondary

MeasureTime frame
Epithelization index. Timepoint: 0, 15, 30. Method of measurement: Maximum diameter at the baseline - Maximum diameter at the end of study)/ Maximum diameter at the baseline * 100.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Atarzadeh

Tehran University of Medical Sciences, department-of-traditional-medicine

dr.atarzadeh@gmail.com+98 71 1626 8875

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026