Hypercholesterolemic. Low-density-lipoprotein-type [LDL] hyperlipoproteinaemia
Conditions
Interventions
Intervention 1: All subjects were provided with a hypo caloric diet in the calorie range of 1500- 2000 for 4 weeks. the intervention group received the hypocaloric diet containing an experimental brea
Prevention
All subjects were provided with a hypo caloric diet in the calorie range of 1500- 2000 for 4 weeks. the intervention group received the hypocaloric diet containing an experimental bread rich in beta-g
All subjects were provided with a hypo caloric diet in the calorie range of 1500- 2000 for 4 weeks. The control group consumed the hypocaloric diet with control bread rich in wheat fiber (at least fiv
Sponsors
Isfahan Cardiovascular Research Institute
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age 25-65 years old; hypercholesterolemia patients who receiving statins for hypercholesterolemia. Exclusion criteria: Diabetes type one or two; hypothyroidism; renal failure; anemia; cholestasis; pancreatic cancer or malignancy; secondary dyslipidemia; used antihypertensive drugs; alcohol; smoked; did regular exercise; had a history of eating disorder; had weight changes (losing or gaining more than three kilogram weight during the three months prior to the study)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lipid Profile. Timepoint: Before and after intervention. Method of measurement: Autoanalyzer.;Fasting blood sugar. Timepoint: Before and after intervention. Method of measurement: Autoanalyzer.;Flow-mediated dilation (FMD). Timepoint: Before and after intervention. Method of measurement: FMD is a noninvasive technique where forearm ischemia is induced by inflating a sphygmomanometer cuff to 50-100 mmHg for five minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body mass index. Timepoint: before and after intervention. Method of measurement: Body mass index (BMI) was calculated as weight divided by height squared.;Hip circumference. Timepoint: before and after intervention. Method of measurement: measured based on standard protocols.;Waist circumference. Timepoint: before and after intervention. Method of measurement: measured based on standard protocols.;Blood pressure. Timepoint: before and after intervention. Method of measurement: after 20-minuterest, in sitting position. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Hamidreza Roohafza
Isfahan Cardiovascular Research Institute
Outcome results
None listed