Febrile Convulsions. Febrile convulsions
Conditions
Interventions
Intervention 1: Intervention group : The patients in the intervention group take 5 mg per kg oral Topiramate per day for a year. To ensure proper use of the drug, the patient is asked to visit the cli
Treatment - Drugs
Intervention group : The patients in the intervention group take 5 mg per kg oral Topiramate per day for a year. To ensure proper use of the drug, the patient is asked to visit the clinic again after
Control group: The patients in the control group take 5 mg per kg oral phenobarbital in two divided doses per day for a year. To ensure proper use of the drug, the patient is asked to visit the clinic
Sponsors
Zahedan University of Medical Sciense
Eligibility
Sex/Gender
All
Age
1 Years to 5 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients aged 6 months to 5 years suffering from febrile convulsion; if the first febrile convulsion occurs under 1 year of age; positive family history of febrile convulsion in first-degree relatives; low grade fever during the first attack (less than 39 °C); short period of time between the onset of fever and convulsion; multiple attacks of seizure; if the first febrile convulsion is complex. Exclusion criteria: patients who have clinical or radiographic signs due to chronic mental disease (MR); patients who were diagnosed with meningitis considering the LP; patients whose seizure caused by electrolyte imbalance; history of a seizure without high temperature; patients who received prophylaxis treatment; patients who developed side effect due to receiving Topiramate.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decreasing the relapse of Febrile Convulsion. Timepoint: After one year. Method of measurement: Clinical assessment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Ali Khaje
Zahedan University of Medical Science
Outcome results
None listed