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Comparison of Therapeutic effect of azithromycin drops and doxycycline capsules on treatment of eyelid inflammation

Comparison between the therapeutic effect of massage and drops of 1% azithromycin with massage and doxycycline 100 mg capsules on the treatment of posterior blepharitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013120515119N2
Enrollment
50
Registered
2014-06-27
Start date
2014-01-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posterior Blepharitis. Blepharitis

Interventions

Intervention 1: Azithromycin 1% drop, produced by Sina Darou Company, 2 drops 2 times a day for 2 days than 1 drop daily for 12 days. Intervention 2: Doxycycline 100 mg Capsule, produced by Razak com
Treatment - Drugs
Azithromycin 1% drop, produced by Sina Darou Company, 2 drops 2 times a day for 2 days than 1 drop daily for 12 days
Doxycycline 100 mg Capsule, produced by Razak company, Once a day for 4 weeks

Sponsors

Vic-Chancellor of Research and Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) patients with posterior blepharitis (b) aged 20 to 50 years, (c) moderate blepharitis Grade 3 Exclusion criteria: (a) blepharitis previously treated, (b) severe blepharitis, (c) concurrent ocular disorders.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Eye dryness. Timepoint: The first visit, 1 week later and at the end of the treatment period. Method of measurement: Shirmer Test.;Eye Pruritus. Timepoint: The first visit, 1 week later and at the end of the treatment period. Method of measurement: Questionnaire.;Corneal or conjunctiva staining. Timepoint: The first visit, 1 week later and at the end of the treatment period. Method of measurement: Slit Lamp.

Secondary

MeasureTime frame
Any side effect such as allergy. Timepoint: The first visit, 1 week later and at the end of the treatment period. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Zandian

Hamadan University of Medical Sciences

m.zandian@umsha.ac.ir+98 81 1838 0090

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026