Efficacy of Vicryl Rapide suture on the reduction of the scar formation after upper jaw surgery

Evaluation of the scar formation using Vicryl rapide and Vicryl suture materials in Le-fort I osteotomy: A triple-blinded randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20131205015665N5

Enrollment

Registered

2020-08-25

Start date

2020-08-31

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clinical evaluation of mucosal scar in maxillary vestibule using vicryl and vicryl rapide suture materials after Le-fort I osteotomy. Surgical instruments, materials and general hospital and personal-use devices (including sutures) associated with adverse incidents

Interventions

Intervention 1: Intervention group 1: Considering an ID number from 1 to 26 for each patient, randomization is done using online computer-based software (http://www.randomization.com). The randomizati

5 mm superior to the mucogingival junction from maxillary right first molar to the maxillary left first molar. after osteotomy and before suturing the incision line, alar base cinch technique using 3-

5 mm superior to the mucogingival junction from maxillary right first molar to the maxillary left first molar. after

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: patients undergoing Le-fort I osteotomy for correction of skeletal deformity

Exclusion criteria

Exclusion criteria: age less than 18 or more than 40 pre-existing scar in vestibular area or history of surgery in maxillary vestibule any systemic and chronic disease which can interfere with wound healing process (i.e. diabetes, kidney and liver diseases) long-term corticosteroid or antibiotic therapy, or immunosuppressor drugs (specially in the last 6 month) congenital or acquired compromising immune system dehydration and malnutrition and associated neural defects (especially vitamin C and zinc deficiency) history of radiotherapy and using cytotoxic drugs tobacco use and alcoholism Fitzpatrick skin classification types I, IV, V, VI Maxillary advancement more than 6 mm history of allergic reaction (known or suspected) to suture materials

Design outcomes

Primary

Measure	Time frame
Mean score of mucosal scarring index from 0 to 10. Timepoint: 4 months after surgery. Method of measurement: using mucosal scarring index consisting of 5 parts of Width, Height or Contour, Color, Suture mark, and Overall appearance; each range from 0 to 2 scores. For reach patient, 3 surgeons will evaluate the tissue and the mean of scores will be reported for the left and right sides for each patient.	—

Measure

Time frame

Mean score of mucosal scarring index from 0 to 10. Timepoint: 4 months after surgery. Method of measurement: using mucosal scarring index consisting of 5 parts of Width, Height or Contour, Color, Suture mark, and Overall appearance; each range from 0 to 2 scores. For reach patient, 3 surgeons will evaluate the tissue and the mean of scores will be reported for the left and right sides for each patient.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMilad Etemadi Shalamzari

Esfahan University of Medical Sciences

etemadi@dnt.mui.ac.ir+98 31 3792 5581

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026