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Evaluation of the effect of green tea extract on the postoperative pain following surgical removal of the impacted mandibular wisdom tooth

Evaluation of the effect of green tea extract on the postoperative pain following surgical removal of the impacted mandibular third molar

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20131205015665N4
Enrollment
32
Registered
2020-07-10
Start date
2018-05-22
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

evaluation of the postoperative pain following application of the green tea-impregnated gauze after surgical extraction of the impacted mandibular third molar. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group 1: All the surgeries will be performed by an experienced surgeon using the same protocol: the povidone-iodine solution will be applied to the surgical site
2% lidocaine?and?1:80,000 epinephrine (Iran, Tehran, Exir) will be used to block the inferior alveolar and long buccal nerves
a mucoperiosteal envelop flap will be created using a standard incision
if needed, bone removal, tooth sectioning, and bone recontouring will be performed with a low-speed hand-piece under sufficient sterile solution irrigation
following tooth removal the socket will be irrigated with 60 ml of saline
the flap will be sutured using 3–0 silk sutures. Green tea extract-impregnated sterile gauze will be used after removing the right or left tooth, according to the randomized order specified before and

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Having bilateral impacted mandibular third molar with the same difficulty based on the spatial direction of the teeth (mesioangular) on preoperative panoramic radiography Having bilateral impacted mandibular third molar with the same difficulty based on the depth of impaction (Pell & Gregory classifications/type B) on preoperative panoramic radiography Having bilateral impacted mandibular third molar with the same difficulty based on the relationship with the anterior border of the ramus (class 1) on preoperative panoramic radiography

Exclusion criteria

Exclusion criteria: having allergy to green tea products being younger than 18 years old or having more than 30 years of age receiving other drugs like antibiotics, analgesics, and herbal therapy for pain/ infection in the last 30 days presence of any kind of lesion (benign or malignant) in the site of surgery before surgery pregnancy and/or lactation systemic health problems presence or history of pain in the maxillofacial region like temporomandibular joint disorder (TMD) or myofascial pain and dysfunction syndrome (MPDS) before surgery presence of pulpitis drug addiction (methamphetamine, ephedrine, or cocaine)

Design outcomes

Primary

MeasureTime frame
Severity of the pain based on Visual analogue scale (VAS). Timepoint: evaluation of the severity of the pain 6, 12, 24, and 48 hours after surgery. Method of measurement: using Visual analogue scale (VAS).;Number of analgesics (ibuprofen) used after surgery. Timepoint: 6, 12, 24,and 48 hours after surgery. Method of measurement: asking the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMilad Etemadi Shalamzari

Esfahan University of Medical Sciences

etemadi@dnt.mui.ac.ir+98 31 3792 5581

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026