Effects of Alkalinization of Bupivacaine (0.5%) on onset of sensory Block in Epidural Ansesthesia in patient with Inguinal herniorrhaphy.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013120115610N1

Enrollment

Registered

2014-01-17

Start date

2013-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inguinal Hernia. Unilateral or unspecified inguinal hernia, without obstruction or gangrene

Interventions

Intervention 1: In Intervention group Epidural Anesthesia performed with 20ml bupivacaien0.5% and0.2ml sodiumbicarbonat 8.4%. Intervention 2: In control Group Epidural Anesthesia Performed With 20ml B

Treatment - Drugs

Placebo

In Intervention group Epidural Anesthesia performed with 20ml bupivacaien0.5% and0.2ml sodiumbicarbonat 8.4%

In control Group Epidural Anesthesia Performed With 20ml Bupivacaine 0.5% and0.2mlFree water.

Eligibility

Sex/Gender

All

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion Critria: Patient age : 25-65 Years, A.S.A(American Sosiety of Anestesiologist) Clasification of Patient : I & II. Exclusion Critria: Refuse of Patient Perception, Disability of sitting position, Neuropathy, Coagulopathy, High I.C.P, Signs of Infection in Lumbosacral region, Cansumption of NSAID and Other Analgesic Drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Onset Time of Sensory Block. Timepoint: After Epidural Anesthesia By one minute. Method of measurement: After Injection by One Minute Evaluetion of Sensoty loss With Attack of Needel to Skin.	—

Secondary

Measure	Time frame
Onset time of motor Block. Timepoint: After Epidural Anesthesia by 5 Minute. Method of measurement: Inability of Flexion of hip joinet.;Blood Presure. Timepoint: By 5minute until 20minute. Method of measurement: Blood Presure in time of Systol and Diastol.;Heart Rate. Timepoint: By 5minute Until 20minute. Method of measurement: Heart Contraction Rate.;Duration of Sensory Block. Timepoint: By 5minute After Surgry. Method of measurement: Duration Time of inability of Sensation of Pain After Attack The needel to Skin.;Duration of Motor Block. Timepoint: By 5minute After Surgry. Method of measurement: Duration Time of inability of flexion Hip Joinet.	—

Measure

Time frame

Onset time of motor Block. Timepoint: After Epidural Anesthesia by 5 Minute. Method of measurement: Inability of Flexion of hip joinet.;Blood Presure. Timepoint: By 5minute until 20minute. Method of measurement: Blood Presure in time of Systol and Diastol.;Heart Rate. Timepoint: By 5minute Until 20minute. Method of measurement: Heart Contraction Rate.;Duration of Sensory Block. Timepoint: By 5minute After Surgry. Method of measurement: Duration Time of inability of Sensation of Pain After Attack The needel to Skin.;Duration of Motor Block. Timepoint: By 5minute After Surgry. Method of measurement: Duration Time of inability of flexion Hip Joinet.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Jamali

Qazvin University Of Medical Sciences.

jjamali@qums.ac.ir+98 28 1333 5800

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026