the efficace of magnesium sulfate in preterm labor pain managment

Comparision of maintenance therapy and continuous intravenous therapy with magnesium sulfate in preterm labor pain management at 24-36 weeks gestation: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013112913932N2

Enrollment

Registered

2013-12-14

Start date

2013-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preterm labour pain. Preterm spontaneous labour with preterm delivery

Interventions

Intervention 1: The patients in group A, will be received 4gr magnesium sulfate in 200cc D/W 5% during 15 to 20 minutes and then infusion of 20 gr magnesium sulfate during 10 hours (2gr/h). Interven

Treatment - Drugs

The patients in group A, will be received 4gr magnesium sulfate in 200cc D/W 5% during 15 to 20 minutes and then infusion of 20 gr magnesium sulfate during 10 hours (2gr/h)

The patients in group B, will be received 4gr magnesium sulfate in 200cc D/W 5% during 15 to 20 minutes and then continues infusion of 2gr/hr magnesium sulfate for 12 hours

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria:gestational age of 24 - 36 weeks;the presence of atleast 4 uterus contraction during 20 min; dilatation below 4 cm; effacement less than 80% Exclusion criteria:coexistense of medical disease such as diabetes mellitus; asthma; cardiovascular disease; preeclampsia; uterine bleeding; rupture of membrane; placenta decolman; intruterine infections; UTI; fetus anomalies; previous preterm labor pain; lack of decreasing uterus contractions during 2 first hr after administration of magnesium sulfate; The patient need to administration of magnesium sulfate after 24 h.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Controlling uterine contraction. Timepoint: during intervention- 24 h after intervention. Method of measurement: checking uterine contraction by hand.;Preterm delivery. Timepoint: just after intervention- 48 h after intervention. Method of measurement: , delivery before 37 weeks of gestation.	—

Secondary

Measure	Time frame
Duration of pregnancy. Timepoint: during and after intervention. Method of measurement: day.;Duration of neonatal admission in NICU. Timepoint: after intervention. Method of measurement: day.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026