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Evaluation of Co-Enzyme Q10 in cardiac pre-procedural injury of ischemic heart diseases patients undergoing angioplasty

A Randomized trial of Co-Enzyme Q10 on Plasma Level of Cardiac Troponin-I and Creatinine Kinase- MB in patients undergoing to angioplasty and stenting.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201311278307N3
Enrollment
90
Registered
2014-02-19
Start date
2014-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischaemic heart diseases. Ischaemic heart diseases

Interventions

Intervention 1: Intervention: In Co-Enzyme Q10 group, all patients will receive totally 300 mg Co-Enzyme Q10 before PCI. Intervention 2: Control: In the control group, Co-Enzyme Q10 will not be admini
Treatment - Drugs
Intervention: In Co-Enzyme Q10 group, all patients will receive totally 300 mg Co-Enzyme Q10 before PCI.
Control: In the control group, Co-Enzyme Q10 will not be administrated. two groups will be given standard treatment.

Sponsors

Vice chancellor for research, Tabriz University of Medical Sciences.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ischemic heart diseases patients; Aged 18-80; undergoing of angioplasty; stent insertion; filling of consent form. Exclusion Criteria: elevation of CK-MB and cTnI 48 hours before PCI; history of CABG during last three months, history of previous MI; Renal dysfunction (creatinine above 2.5 mg/dl); unsuccessful PCI; Acute MI; cardiogenic shock; dialysis; Pregnancy; inability in filling and understanding of the consent form; unconsented patients; patients who want to discontinue the study at any time.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
CK-MB level. Timepoint: 12 hours before and 8 and 24 hours after angioplasty. Method of measurement: ELISA kits.;CTnI level. Timepoint: 12 hours before and 8 and 24 hours after angioplasty. Method of measurement: ELISA kits.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026