root canal therapy

Evaluation of Clinical and Radiographic success rate of Lesion Sterilization and Tissue Repair in non vital primary molars : a Clinical Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013112615558N1

Enrollment

Registered

2016-07-03

Start date

2016-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulpectomy.

Interventions

Intervention 1: ]ntervention: pulp therapy with 3 Mix Antibiotic paste, Ciprofloxacin, Metronidazole and Minocycline, volume ratio 1:3:3 respectively, once utilization. Intervention 2: Control: st

Treatment - Other

Treatment - Drugs

]ntervention: pulp therapy with 3 Mix Antibiotic paste, Ciprofloxacin, Metronidazole and Minocycline, volume ratio 1:3:3 respectively, once utilization

Control: standard pulpectomy

Eligibility

Sex/Gender

All

Age

4 Years to 8 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: children with no systemic disease; mandibular second primary molar tooth with periradicular radiolucency Exclusion criteria: children with systemic and immunosuppressed diseases and sensitive to antibiotic drugs; hyperemic pulp

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Clinical success. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: examination and observation, expression by pateint.;Radiographic success. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: radiographic feature.	—

Secondary

Measure	Time frame
Pain. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: expression by patient.;Fistula. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: examination and observation.;Abscess. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: examination and observation.;Tenderness to percussion. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: examination and observation.;New radiolucent lesion. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: radiographic feature.;Change in primary lesion. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: radiographic feature.;Internal or external resorption. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: radiographic feature.	—

Measure

Time frame

Pain. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: expression by patient.;Fistula. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: examination and observation.;Abscess. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: examination and observation.;Tenderness to percussion. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: examination and observation.;New radiolucent lesion. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: radiographic feature.;Change in primary lesion. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: radiographic feature.;Internal or external resorption. Timepoint: 2 and 6 and 12 months after intervention. Method of measurement: radiographic feature.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHoma Noorollahian

Mashhad dental school

noorollahianh@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026