Obesity. Obesity due to excess calories,
Conditions
Interventions
Intervention 1: Intervention group: Daily consumption of 3 gram taurine ( cap 1 gram ) simultaneously with weight loss diet for 8 weeks. Intervention 2: Control group: Daily consumption of 3 cap place
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Women aged 18 to 50 years old Body mass index between 30 to 40
Exclusion criteria
Exclusion criteria: Pregnancy and breast feeding Menopause Food allergy Having surgical operation to weight loss Having weight loss over the past six months Consumption of multivitamin/mineral supplements, herbal supplements or weight-loss drugs Having a special diet Having a history of cancer, acute or chronic renal Failure, acute or chronic hepatic failure, thyroid disorder and gastrointestinal diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum level of fibroblast growth factors FGF19. Timepoint: Before and 8 months after intervention. Method of measurement: ELISA.;Serum level of fibroblast growth factors FGF21. Timepoint: Before and 8 months after intervention. Method of measurement: ELISA.;Serum level of ß-Klotho co-receptor. Timepoint: Before and 8 months after intervention. Method of measurement: ELISA.;Serum level of leptin. Timepoint: Before and 8 months after intervention. Method of measurement: ELISA.;Serum level of adiponectin. Timepoint: Before and 8 months after intervention. Method of measurement: ELISA.;Serum level of High sensitivity C-reactive protein ( hs-CRP). Timepoint: Before and 8 months after intervention. Method of measurement: ELISA.;Serum level of insulin. Timepoint: Before and 8 months after intervention. Method of measurement: ELISA.;Lipid profile. Timepoint: Before and 8 months after intervention. Method of measurement: Colorimetric enzymatic method (Pars Azmun).;Alanine transaminase, Aspartate transaminase and Gamma-glutamyltransferase. Timepoint: Before and 8 months after intervention. Method of measurement: Colorimetric enzymatic method (Pars Azmun).;Body composition. Timepoint: Before, 4 weeks and 8 weeks after intervention. Method of measurement: Bioelectrical impedance analysis.;Waist circumference. Timepoint: Before, 4 weeks and 8 weeks after intervention. Method of measurement: Tape metre.;Fasting blood sugar (FBS). Timepoint: Before and 8 months after intervention. Method of measurement: Colorimetric enzymatic method (Pars Azmun).;Body weight. Timepoint: Before, 4 weeks and 8 weeks after intervention. Method of measurement: Scale.;Homeostatic Model Assessment for Insulin Resistance (HOMA-IR). Timepoint: Before and 8 months after intervention. Method of measurement: HOMA-IR: [fasting insulin Mu/ml × fasting glucose mg/dl]/405. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Asadi
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed