The effect of paracetamol for pain control after knee arthroscopy surgeries.

Evaluation of the effect sole paracetamol for pain control after knee arthroscopy surgeries

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013112415515N1

Enrollment

Registered

2014-09-23

Start date

2014-09-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pain management after knee arthroscopy. Other acute postprocedural pain

Interventions

Intervention 1: In the study group, Intravenous infusion of 2 g paracetamol. Intervention 2: In the control group, Morphine PCA pump.

Prevention

In the study group, Intravenous infusion of 2 g paracetamol

In the control group, Morphine PCA pump

Eligibility

Sex/Gender

All

Age

78 Years to 33 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 15-60 yr;ASA Class I- II; Arthroscopic knee surgery under epidural anesthesia. Exclusion criteria: Taking any pain medication 24 hours before surgery; Patients unable or unwilling to use patient-controlled analgesia (PCA); Liver failure; Kidney failure; Severe cardiopulmonary; Coagulopathy; Obesity morbid; History of postoperative nausea and vomiting; History of migraine; History of complications during and after surgery; Postoperative complications in the first 24 hours that may require intervention; Known allergies; Sensitivity or contraindication for opioid and non opioid drugs; Pregnancy and lactation; Substance abuse.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain score. Timepoint: Arrival in the recovery room, 15 and 30 min, 1, 2, 4, 6, 12, 18 and 24 hours after study drug administration. Method of measurement: Visual analog scale.	—

Secondary

Measure	Time frame
Patient satisfaction. Timepoint: First 24 hours after surgery. Method of measurement: Based on the patient's questions.;Amount of analgesia used. Timepoint: First 24 hours after surgery. Method of measurement: Based on the patient's questions.;Side effect. Timepoint: First 24 hours after surgery. Method of measurement: Based on the patient's questions.;Nausea and vomiting. Timepoint: Arrival in the recovery room, 15 and 30 min, 1, 2, 4, 6, 12, 18, 24 h after initiation of study drug. Method of measurement: Based on the score of 1-4.;Sedation score. Timepoint: Arrival in the recovery room, 15 and 30 min, 1, 2, 4, 6, 12, 18, 24 h after initiation of study drug. Method of measurement: Ramsay scale.	—

Measure

Time frame

Patient satisfaction. Timepoint: First 24 hours after surgery. Method of measurement: Based on the patient's questions.;Amount of analgesia used. Timepoint: First 24 hours after surgery. Method of measurement: Based on the patient's questions.;Side effect. Timepoint: First 24 hours after surgery. Method of measurement: Based on the patient's questions.;Nausea and vomiting. Timepoint: Arrival in the recovery room, 15 and 30 min, 1, 2, 4, 6, 12, 18, 24 h after initiation of study drug. Method of measurement: Based on the score of 1-4.;Sedation score. Timepoint: Arrival in the recovery room, 15 and 30 min, 1, 2, 4, 6, 12, 18, 24 h after initiation of study drug. Method of measurement: Ramsay scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Masoud Hashemi MD.

Akhtar Hospital

dr.hashemi@sbmu.ac.ir+98 21 2261 2252

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026