The effect of Peppermint Aroma on Nausea and Vomiting in Patients with Acute Myocardial Infarction

The effects of Peppermint essence on nausea and vomiting in patients with acute myocardial infarction

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013112415507N1

Enrollment

126

Registered

2014-05-21

Start date

2014-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction. I21.0,I21.1,I21.2,I21.3,I21.4,I21.9

Interventions

Intervention 1: Intervention group: Peppermint scented gauze pads will be prepared by placing 0.2 mL of essential oil of peppermint. These pads will be attached to the patients’ clothes for 24 hours.

Treatment - Other

Placebo

Intervention group: Peppermint scented gauze pads will be prepared by placing 0.2 mL of essential oil of peppermint. These pads will be attached to the patients’ clothes for 24 hours.

Control group: placebo pads will be prepared by 0.2 mL of isotonic saline. These pads will be attached to the patients’ clothes for 24 hours.

Eligibility

Sex/Gender

All

Age

30 Years to 88 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:30-88 years old, diagnosis of acute myocardial infarction according to clinical signs, electrocardiography and cardiac biomarkers that confirmed by the cardiologist. Exclusion criteria: cardiogenic shock, acute asthma, chronic obstructive pulmonary disease, congestive heart failure class III or IV, cardiopulmonary resuscitation, recurrent myocardial infarction, and allergy to peppermint compounds.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Nausea. Timepoint: 0-2-4-6-8-10-16-24. Method of measurement: Visual Analog Scale for Nausea.;Vomiting. Timepoint: 0-2-4-6-8-10-16-24. Method of measurement: Check List.	—

Secondary

Measure	Time frame
Pulse Rate. Timepoint: 0-2-4-6-8-12-16-18-24. Method of measurement: Pulse Counting.;Respiratory Rate. Timepoint: 0-2-4-6-8-12-16-18-24. Method of measurement: Respiratory Rate Counting.;Blood Pressure. Timepoint: 0-2-4-6-8-12-16-18-24. Method of measurement: Millimeters of Mercury, Using Manometer and Blood Pressure Cuff.;Temperature. Timepoint: 0-2-4-6-8-12-16-18-24. Method of measurement: Thermometer.	—

Measure

Time frame

Pulse Rate. Timepoint: 0-2-4-6-8-12-16-18-24. Method of measurement: Pulse Counting.;Respiratory Rate. Timepoint: 0-2-4-6-8-12-16-18-24. Method of measurement: Respiratory Rate Counting.;Blood Pressure. Timepoint: 0-2-4-6-8-12-16-18-24. Method of measurement: Millimeters of Mercury, Using Manometer and Blood Pressure Cuff.;Temperature. Timepoint: 0-2-4-6-8-12-16-18-24. Method of measurement: Thermometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Mohsenifard

Arak University of Medical Sciences

m.mohseni@arakmu.ac.ir+98 86 3368 6449

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026