Bipolar disorder. Bipolar affective disorder
Conditions
Interventions
Intervention 1: The intervention group received one omega-3 capsule (manufactured by Natures Factor company from America) daily for 3 months. Intervention 2: The control group was given 1000 mg placeb
Treatment - Drugs
Placebo
The intervention group received one omega-3 capsule (manufactured by Natures Factor company from America) daily for 3 months
The control group was given 1000 mg placebo daily for 3 months.
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: Presence of bipolar disorders type I in mania phase or mixed based on DSM-IV. criteria, patient satisfaction and his head confirming to be treated by lithium and olanzapine. exclusion criteria: Mental retarded patients based on clinical diagnosis or IQ less than 70 using related tests; patients with pervasive developmental disorders based on history and clinical diagnosis; Patients requiring ECT or other treatments except lithium mood stabilizer (like other mood stabilizers) and olanzapine because of symptoms severity based on clinical assessment by a psychiatrist, drug abuse or drug dependence at least three months prior to the survey; pregnancy, the possibility of suicide, risk of harm to others; patients with severe complications of omega-3 usage such as disruption of bleeding time.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of illness. Timepoint: At baseline and 3 months after study. Method of measurement: Based on questionnaire.;Level of illness. Timepoint: At baseline and 3 months after study. Method of measurement: Based on questionnaire and at least 50% reduction in Yang scale. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed