Helicobacter Pylori Infection. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention 1: Intervention group: Patients receiving 14 days high-dose triple therapy of esomeprazole and amoxicillin & bismuth regimen for Helicobacter pylori eradication. Intervention 2: Control
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria : ages between 18 and 80 years who have H. pylori positive and have endoscopic findings of gastric ulcer duodenal ulcer gastritis duodenitis histologic evidence of intestinal metaplasia.
Exclusion criteria
Exclusion criteria: Pregnant or nursing women, those with a history of upper GI surgery major cardiac diseases major lung diseases major liver diseases history of previous H. pylori eradication regimen history of known side effects to the protocol drugs major renal diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori infection. Timepoint: Before the start of the Helicobacter pylori eradication regimen. Method of measurement: Through pathology before starting of Helicobacter pylori treatment regimen. | — |
Secondary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication. Timepoint: 8 weeks after end of HP eradication treatment. Method of measurement: Helicobacter pylori stool antigen test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Mohammad Valizadeh Toosi
Mazandaran University of Medical Sciences
Outcome results
None listed