Peptic ulcer disease and H pylori infection. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
Conditions
Interventions
Intervention 1: Intervention group: In this study, patients in the intervention group used esmoprazole capsules 40 mg three times a day and amoxicillin 500 mg capsules three times a day for 14 days. I
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: People with peptic ulcer or gastro-duodenal erosion Helicobacter pylori infection on a pathological biopsy or Rapid urease test who have not previously received a Helicobacter pylori eradication regimen
Exclusion criteria
Exclusion criteria: Age under 18 years Pregnancy and lactation Concomitant use of anticoagulants, corticosteroids or ketoconazole atients who have a history of gastric surgery Patients with a confirmed history of severe heart or lung failure, chronic kidney failure, chronic liver disease or a history of cancer. History of drug allergy to the drugs of this study Previous history of Helicobacter pylori eradication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori infection rat. Timepoint: Evaluation of Helicobacter pylori infection at the beginning of the study and then 8 weeks after receiving the desired treatment regimen. Method of measurement: Measurement of Helicobacter pylori infection variable by pathology at the beginning of the study and confirmation of eradication at the end of the study by fecal antigen method. | — |
Secondary
| Measure | Time frame |
|---|---|
| H pylori infection eradication. Timepoint: initiation of study and 8 weeks after end of treatment. Method of measurement: At the beginning of treatment by pathology and at the end of treatment by fecal antigen of Helicobacter pylori. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Mohammad Valizadeh Toosi
Mazandaran University of Medical Sciences
Outcome results
None listed