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Parallel randomized clinical trial on the effects of citrus aurantifolia extract on components of metabolic syndrome and markers of endothelial dysfunction among overweight children and adolescents aged 9-18

Parallel randomized clinical trial on the effects of citrus aurantifolia extract on components of metabolic syndrome and markers of endothelial dysfunction among overweight children and adolescents aged 9-18

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201311231434N11
Enrollment
60
Registered
2014-01-01
Start date
2013-11-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity. Obesity due to excess calories

Interventions

Intervention 1: citrus aurantifolia extract (3 capsule/day) for intervention group. Intervention 2: placebo (corn starch) (3 capsule/day) for control group.
Treatment - Drugs
citrus aurantifolia extract (3 capsule/day) for intervention group
placebo (corn starch) (3 capsule/day) for control group

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
9 Years to 18 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age (9-18 years); and body mass index (BMI) above 85th centile for age and sex. Exclusion criteria: Hypothyroidism; medical therapy for dyslipidemia; smoking or exposure to tobacco.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Body mass index. Timepoint: baseline and at the end of study. Method of measurement: measurment.—

Secondary

MeasureTime frame
Serum triglyceride. Timepoint: baseline and at the end of study (after one month). Method of measurement: labaratory.;Total cholesterol. Timepoint: baseline and at the end of study (after one month). Method of measurement: labaratory.;High-density lipoprotein. Timepoint: baseline and at the end of study (after one month). Method of measurement: labaratory.;Low-density lipoprotein. Timepoint: baseline and at the end of study (after one month). Method of measurement: labaratory.;Fasting blood glucose. Timepoint: baseline and at the end of study (after one month). Method of measurement: labaratory.;Waist circumference. Timepoint: baseline and at the end of study (after one month). Method of measurement: elastic tape.;Blood pressure. Timepoint: baseline and at the end of study (after one month). Method of measurement: barometer.;Intercellular adhesion molecule (ICAM). Timepoint: baseline and at the end of study (after one month). Method of measurement: labaratory.;Vascular cell adhesion molecule (VCAM). Timepoint: baseline and at the end of study (after one month). Method of measurement: labaratory.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Maryam Kargar

Isfahan University of Medical Sciences

Maryam kargar9 @ yahoo.com+98 31 1387 6006

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026