Survey the effects of antifungal medicines for treatment of napkin dermatitis

A comparative trial of three medicines including: Nystatin,Cloterimazole and Mupirocine to treat a diaper dermatitis.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013112215458N1

Enrollment

164

Registered

2015-03-26

Start date

2013-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diaper(Napkin) Dermatitis. Diaper or Napkin: erythema rash

Interventions

Intervention 1: Control Group: Zinc Oxide Cream four times a day plus Hydrocortison Cream three times a day for one week . 1FTU(one Finger Tube Unite equal to Distal phalanx of index finger )fo

Treatment - Drugs

Control Group: Zinc Oxide Cream four times a day plus Hydrocortison Cream three times a day for one week . 1FTU(one Finger Tube Unite equal to Distal phalanx of index finger )for an area of s

Intervention Group 1: Clotrimazol Cream two times daily plus Hydrocortisone Cream Three times a day for one week . 1FTU(one Finger Tube Unite equal to Distal phalanx of index finger )for an area

Intervention Group 2: Nystatin Cream two times daily plus Hydrocortisone Cream Three times a day for one week . 1FTU(one Finger Tube Unite equal to Distal phalanx of index finger )for an area of

Intervention Group 3: Mupirocin Cream four times daily plus Hydrocortisone Cream Three times a day for one week . 1FTU(one Finger Tube Unite equal to Distal phalanx of index finger )for an area o

Eligibility

Sex/Gender

All

Age

No minimum to 2 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 1. Age 0-2 years 2.minimum severity score 1 3 duration less than 6 weeks Exclusion Criteria: 1.Duration of disease more than 6 weeks 2. Another Perineal diseases like Psoriasis, Perineal infection , Perineal or genital wart, contact allergic dermatiti 3. congenital immunodeficiency diseases 4.Previous Treatment with clotrimazole,Nystatin,Mupirocine,hydrocortison except zinc oxide within 2 weeks before enrollment 5.Allergy to Clotrimazol, Nystatin, Zinc oxide,Mupirocine,hyrdocortison 6.treatment with systemic corticosteroid,Antifungal or Antibiotic during study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Sevierty of dermatitis To determine severity, each of skin lesion received one point and according to the scores divided patients in three category: mild with score of 1, moderate with score of 2 and severe with score of 3 and more. Timepoint: baseline and one week after study. Method of measurement: According to response to treatment they would be divided in three groups with the same scale we used to determine severity of dermatitis. Complete relief ( score zero) ,partially treated ( score 1-2), no response (score 3 and more).	—

Measure

Time frame

Sevierty of dermatitis To determine severity, each of skin lesion received one point and according to the scores divided patients in three category: mild with score of 1, moderate with score of 2 and severe with score of 3 and more. Timepoint: baseline and one week after study. Method of measurement: According to response to treatment they would be divided in three groups with the same scale we used to determine severity of dermatitis. Complete relief ( score zero) ,partially treated ( score 1-2), no response (score 3 and more).

—

Secondary

Measure	Time frame
Medication side effect, extension of dermatitis. Timepoint: baseline and 1 week after study. Method of measurement: Checklist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mohammad Mehdi Houshmandi

Hormozgan Univesity of Medical siences

mhoushmandi@gmail.com+98 76 1666 6240

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026