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Effect of Vaginal Sildenafil on Female Sexual Function Index and Sexual Satisfaction

Effect of Vaginal Sildenafil on Female Sexual Function Index and Sexual Satisfaction, in Premenopause and Postmenopause Women

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013112015461N1
Enrollment
100
Registered
2017-11-07
Start date
2015-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female Sexual Dysfunction and Satisfaction.

Interventions

Intervention 1: Taking 100 mg sildenafil tablets 1 hour before each vaginal intercourse for 3 months. Intervention 2: Taking sildenafil tablets 1 hour before sexual intercourse for 3 months.
Treatment - Drugs
Placebo
Taking 100 mg sildenafil tablets 1 hour before each vaginal intercourse for 3 months
Taking sildenafil tablets 1 hour before sexual intercourse for 3 months

Sponsors

Vice chancellor for research, Tarbiyat Modares Univercity
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 45-65 years old in post menopause and 25-45 years old in premenstrual women; Being sexually active; at least 12 month amenorah in post menopause women; no surgical menopause; no hormone replacement therapy; BMI= 19.8-30; no high BP; no drug use;no smoking; no alcohol; no liver; heart; thyroid disease or diabetic; no chronic disease; no cancer or precancerous disease; no vaginal bleeding;no endometrial hyperplasia or polyp; no pelvic radiation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Improvement of female sexual satisfaction and sexual function. Timepoint: Three months after the intervention. Method of measurement: Complete Sexual Function Questionnaire (FSFI) and Sexual Satisfaction (ISS) before and after intervention.

Secondary

MeasureTime frame
Effect on Endometrial Thickening and Interaepitelial Maturation Index in Menopause Women. Timepoint: Three Months after the Intervention. Method of measurement: Vaginal Sonography and Pap smear.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzar Mashhoori Vayghan

Tarbiat Modares Univercity

azar.mashhoori@modares.ac.ir, azar.mashhoory@gmail.com+98 21 6641 5778

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026