Comparison of Nitrous Oxided and Ketamin Sedative Analgesic Effect for Pain Control.

Comparison of Sedative Analgesic Effect of Nitrous Oxide versus Ketamine in limb fracture Pain Control , a Pilot Study. Golestan hospital emergency ward

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013111815446N1

Enrollment

Registered

2014-05-29

Start date

2013-11-28

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Local anesthesia. Local anaesthetics

Interventions

Intervention 1: Intervention group: nitrous oxide 50:50 intake. Intervention 2: Control group: recieve ketamin 0.3 mg/kg intravenus.

Treatment - Drugs

Intervention group: nitrous oxide 50:50 intake

Control group: recieve ketamin 0.3 mg/kg intravenus

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion Criteria: any limbs fractures who are seeking for Pain Control. Exclusion Criteria: COPD; liver disease; head injury; loss of consciousness; lung injury; asthma and patient disagreement.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain relief. Timepoint: Baseline, fifth, tenth, fifteenth minutes. Method of measurement: VAS score.	—

Secondary

Measure	Time frame
Decrease blood pressure. Timepoint: Baseline, fifth, tenth, fifteenth minutes since start of drug give. Method of measurement: Patient monitoring- blood pressure measurement.;Respiratory faillue. Timepoint: Baseline, fifth, tenth, fifteenth minutes since start of drug give. Method of measurement: Patient monitoring- blood pressure measurement.;Vomiting. Timepoint: Baseline, fifth, tenth, fifteenth minutes since start of drug give. Method of measurement: Patient monitoring- blood pressure measurement.	—

Measure

Time frame

Decrease blood pressure. Timepoint: Baseline, fifth, tenth, fifteenth minutes since start of drug give. Method of measurement: Patient monitoring- blood pressure measurement.;Respiratory faillue. Timepoint: Baseline, fifth, tenth, fifteenth minutes since start of drug give. Method of measurement: Patient monitoring- blood pressure measurement.;Vomiting. Timepoint: Baseline, fifth, tenth, fifteenth minutes since start of drug give. Method of measurement: Patient monitoring- blood pressure measurement.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hassan Motamed

Ahvaz University of Medical Sciences

motamed-h@ajums.ac.ir+98 61 1374 3079

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026