Effect Of Glucagon on Treatment Of Acute Severe Asthma Attack

Evaluation Of Clinical And Peak Flow Metric Effect Of Intravenous Glucagon On Treatment Of Acute Severe Asthma Attack

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20131118015446N13

Enrollment

Registered

2018-02-17

Start date

2017-10-23

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma. Asthma

Interventions

Intervention 1: Intravenous injection of 1 mg of glucagon over 1minute for case group. Intervention 2: Intravenous injection of 1 mL normal saline for control group.

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Severe asthma attack Age between 18 and 55

Exclusion criteria

Exclusion criteria: History of diabetes mellitus Smoking Ischemic heart disease Emphysema or chronic bronchitis Insulinoma pheochromocytoma Current oral or injectable corticosteroids, pregnancy Pregnancy Lactation Need for intubation

Design outcomes

Primary

Measure	Time frame
Peak Expiratory Flow Rate (PEFR). Timepoint: At 0, 10, 15, 30, 45 ,60 minutes after intervention. Method of measurement: Litre/minute, by spirometry.;FEV1. Timepoint: At 0, 10, 15, 30, 45 ,60 minutes after intervention. Method of measurement: Litre, by spirometry.	—

Secondary

Measure	Time frame
Respiratory rate. Timepoint: At 0 and 60 minutes after intervention. Method of measurement: Counting of respiration in one minute.;Pulse rate. Timepoint: At 0 and 60 minutes after intervention. Method of measurement: Counting of pulse in one minute.;Blood pressure. Timepoint: At 0 and 60 minutes after intervention. Method of measurement: mmHg, by sphygmomanometer.;Blood glucose. Timepoint: At 0 and 20 minutes after intervention. Method of measurement: mg/dL, by glucometer.;Blood oxygen saturation levels (SpO2). Timepoint: At 0 and 60 minutes after intervention. Method of measurement: Percentage, by pulse oximeter.	—

Measure

Time frame

Respiratory rate. Timepoint: At 0 and 60 minutes after intervention. Method of measurement: Counting of respiration in one minute.;Pulse rate. Timepoint: At 0 and 60 minutes after intervention. Method of measurement: Counting of pulse in one minute.;Blood pressure. Timepoint: At 0 and 60 minutes after intervention. Method of measurement: mmHg, by sphygmomanometer.;Blood glucose. Timepoint: At 0 and 20 minutes after intervention. Method of measurement: mg/dL, by glucometer.;Blood oxygen saturation levels (SpO2). Timepoint: At 0 and 60 minutes after intervention. Method of measurement: Percentage, by pulse oximeter.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hassan Motamed

Ahvaz Jundishapur University Of Medical Science

motamed-h@ajums.ac.ir+98 61 3374 3099

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026