Rheumatoid arthritis. Seropositive rheumatoid arthritis
Conditions
Interventions
Intervention 1: Intervention group: Sesamine supplement, 200 mg caps per day for 6 weeks. Intervention 2: Placebo group: placebo caps for 6 weeks.
Treatment - Drugs
Intervention group: Sesamine supplement, 200 mg caps per day for 6 weeks
Sponsors
Vice chancellor for research, Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria: Willing to participate in study; Clinical diagnosis of rheumatoid arthritis (meeting the American college of rheumatology 1987 criteria); No smoking or addiction; No drug type and dose fluctuation since 1 month prior to the study and during intervention period ; Not having severe cardiovascular; hepatic; kidney; gastrointestinal; thyroid; parathyroid diseases; diabetes and inflammation; Not using medications except for AR conventional drugs; No pregnancy or lactation Exclusion criteria: developing illnesses which need particular cures or interfere with intervention such as increasing the disease activity or trauma; alcoholic; sensitivity to sesame
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total antioxidant capacity (TAC). Timepoint: Before the intervention and 6 weeks after intervention. Method of measurement: ELISA. | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-alpha. Timepoint: Before the intervention and 6 weeks after intervention. Method of measurement: ELISA.;Interlukin 6. Timepoint: Before the intervention and 6 weeks after intervention. Method of measurement: ELISA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Majid Mohamadshahi
Ahvaz Jundishapur University of medical sciences
Outcome results
None listed