Effects of vitamin D on athletes

Effects of vitamin D supplementation on serum levels of adipose tissue browning endocrine regulators, anabolic hormone and exercise performance in male athletes

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20131117015424N3

Enrollment

Registered

2018-06-07

Start date

2018-09-23

Completion date

Unknown

Last updated

2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Athletes.

Interventions

Intervention 1: Intervention group: Daily intake of vitamin D supplement with a dose of 2000 international unit of Zahrawi company (Iran) for 12 weeks. Intervention 2: Control group: Daily intake of a

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Intention to participate BMI between 18.5 to 29.9 Vo2max between 40-60 ml/kg/min Regular physical activity for at least three times per week each time

Exclusion criteria

Exclusion criteria: No intention to participate Presence of metabolic diseases Presence of diagnosed renal (acute or chronic) and bone disease Smoking Using other supplements at the beginning of the study or during past 3 months

Design outcomes

Primary

Measure	Time frame
Serum levels of Fibroblast Growth Factor-21. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of Bone morphogenetic protein 4. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of meteorin-like. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of interleukin-15. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of Growth hormone. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of Insulin-like growth factor 1. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of testosterone. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Aerobic performance. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: By estimating the maximal oxygen uptake (Vo2 max) using the Bruce test.;Anaerobic performance. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Be determined on the basis of 30-second Wingate test using a Monark bike.	—

Measure

Time frame

Serum levels of Fibroblast Growth Factor-21. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of Bone morphogenetic protein 4. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of meteorin-like. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of interleukin-15. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of Growth hormone. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of Insulin-like growth factor 1. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of testosterone. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Aerobic performance. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: By estimating the maximal oxygen uptake (Vo2 max) using the Bruce test.;Anaerobic performance. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Be determined on the basis of 30-second Wingate test using a Monark bike.

—

Secondary

Measure	Time frame
Serum levels of cortisol. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of Parathyroid hormone. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of 25-hydroxy vitamin D. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.	—

Measure

Time frame

Serum levels of cortisol. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of Parathyroid hormone. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.;Serum levels of 25-hydroxy vitamin D. Timepoint: pre-intervention and after 12 weeks of intervention. Method of measurement: Using enzyme-linked immunosorbent assay (ELISA) kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Mohamadshahi

Ahvaz University of Medical Sciences

mohamadshahi-m@ajums.ac.ir+98 912 439 2836

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026