Comparison of diclofenac and acetaminophen in the managment of pain after back surgery.

Comparison of diclofenac and acetaminophen combined with patient controlled analgesia, in the managment of pain after laminectomy surgery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201311168768N3

Enrollment

100

Registered

2013-12-20

Start date

2013-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute postoperative pain. Acute pain

Interventions

Intervention 1: Intervention group: Diclofenac suupp 100mg immediately before induction of anesthesia and 12 hours after surgery, infusion of 100 cc normal saline 15 minutes before the end of the surg

Treatment - Drugs

Intervention group: Diclofenac suupp 100mg immediately before induction of anesthesia and 12 hours after surgery, infusion of 100 cc normal saline 15 minutes before the end of the surgery and 12 hours

Control group: will recieve placebo suppository immediately before induction of anesthesia and 12 hours after surgery, infusion of 1 gram intravenous acetaminophen in 100 cc normal saline 15 minutes

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: Patients candidate for laminectomy with American Society of Anesthesiologists ( ASA ) class I, II Exclusion criteria: Patients with Coagulation disorders, seizure, Asthma, renal or hepatic disease, addiction to opioids or alchohol, sensitivity to NSAIDS or acetaminophen, peptic ulcer disease, opium or NSAIDs use in recent 24 hr, surgery time more than 150 minutes and patient refusal

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain score. Timepoint: In recovery, 6 hours after surgery, 12 hours after surgery, 24 hours after surgery. Method of measurement: Visual Analogue Scale.;Total dose of narcotic used in patient controlled analgesia. Timepoint: 24 hours after surgery. Method of measurement: Observation of PCA pomp and calculating the used narcotic by microgram.;Patient satisfaction. Timepoint: 24 hours after surgery. Method of measurement: Questionare.;Total dose of Adjuvant analgesic. Timepoint: 24 hours after surgery. Method of measurement: With questionare and by miligram.	—

Measure

Time frame

Pain score. Timepoint: In recovery, 6 hours after surgery, 12 hours after surgery, 24 hours after surgery. Method of measurement: Visual Analogue Scale.;Total dose of narcotic used in patient controlled analgesia. Timepoint: 24 hours after surgery. Method of measurement: Observation of PCA pomp and calculating the used narcotic by microgram.;Patient satisfaction. Timepoint: 24 hours after surgery. Method of measurement: Questionare.;Total dose of Adjuvant analgesic. Timepoint: 24 hours after surgery. Method of measurement: With questionare and by miligram.

—

Secondary

Measure	Time frame
Nausea and vomiting. Timepoint: In recovery, 6 hours after surgery, 12 hours after surgery, 24 hours after surgery. Method of measurement: Questionare.;Sedation score. Timepoint: At the end of the surgery, after 24 hours. Method of measurement: By using Ramsy sedation scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahshid Nkooseresht M.D

Hamadan University of Medical Sciences

nikooseresht@umsha.ac.ir+98 81 1264 0049

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026