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Evaluation and comparisson of Defli oil and Diclofenac gel in patients with knee osteoartheritis

Evaluation and comparisson of N.oleander and Diclofenac gel in patients with knee osteoartheritis : A randomized, double-blind, controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013111615413N1
Enrollment
60
Registered
2014-02-12
Start date
2013-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of knee. Primary arthrosis of other joints

Interventions

Intervention 1: Group I: receive topical consumption of defli oil. Every 8 hour on all of site of knee for 30 days for 30days. Intervention 2: receive topical consumption of Diclofenac gel. Every 8 ho
Treatment - Drugs
Group I: receive topical consumption of defli oil. Every 8 hour on all of site of knee for 30 days for 30days
receive topical consumption of Diclofenac gel. Every 8 hour on all of site of knee for 30 days

Sponsors

Dr. Minaei; Vice chancellor for research Traditional Medicine Faculty of Tehran University of Medica
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Out-patients aged 50-80 years who suffer osteoarthritis based on clinical and radiological criteria of ACR included participants. Exclusion criteria: Secondary osteoarthritis; trauma; Endocrine disease(hyperthyroid,hypothyroid ,Diabet); Metabolic disease; other arthritis disease; corticosteroid usage; Joint replacement; concomitant usage in glucosamine and chondroitin sulfate; Intra-articular injection during last 3 months; usage of muscle relaxants drugs; pregnancy; anti-depression; patients suffering from heart; lung; liver; kidney and peptic ulcer and finally patients with proven hypersensitivity to drugs used in this study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Before and after the treatment. Method of measurement: WOMAC questionnaire.;Stifness. Timepoint: Before and after the treatment. Method of measurement: WOMAC questionnaire.

Secondary

MeasureTime frame
Physical function. Timepoint: befor and after intervention. Method of measurement: questionnaire WOMAC.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Askarfarashah

Traditional Medicine Faculty, Tehran University of Medical Sciences

askarfarashah.itm@gmail.com+98 21 5560 1274

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026