Diabetes Mellitus. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group was given 0.5 U/kg insulin which half of this dose given as NPH and other half given as regular insulin in three divided dose( basal/bolus Insulin). Intervention 2
Treatment - Drugs
Intervention group was given 0.5 U/kg insulin which half of this dose given as NPH and other half given as regular insulin in three divided dose( basal/bolus Insulin)
Control group was given Slidng Scale Insulin 4 time a day when their glucose be more than 140 mg/dl.
Sponsors
Vice chancellor for research, Tabriz University of Medical Sciences.
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients who admitted with cardiovascular Diseases; with history of diabetes more than 3 months; blood glucose of 140-400 mg/dl; Hgb A1C more than 6.5%; Age 18-80; who can eat; Patients Giving oral antiglycemic agent; patients who give insulin with doses of 0.4 IU/kg/day or lower. Exclusion Criteria: Hyperglycemia without the known Diabetes; CABG; severe Liver Diseases; Renal dysfunction (creatinine above 3 mg/dl); History of diabetic ketoacidosis; Pregnancy; inability in filling and understanding the consent form; unconsented patients; patients who want to discontinue the study at any time.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood level of glucose in each group. Timepoint: Every morning before breakfast. Method of measurement: Blood glucose measurement (glucometry).;Blood Glucose level before each meals. Timepoint: Every day before each meals. Method of measurement: Glucometry.;Recurrent MI. Timepoint: During hospitalization. Method of measurement: Medical record, Lab findings, ECG.;Severe hypoglycemia epizodes. Timepoint: Before each meals. Method of measurement: Glucometry.;ICU admission. Timepoint: During hospitalization. Method of measurement: Medical record.;Mortality rate. Timepoint: During hospitalization. Method of measurement: Medical record.;Heart Failure. Timepoint: During hospitalization. Method of measurement: Echocardiography. | — |
Secondary
| Measure | Time frame |
|---|---|
| CCU Admission. Timepoint: During the time of admission. Method of measurement: Medical records.;Mild hypoglycemia epizodes. Timepoint: Before each meals. Method of measurement: Glucometry.;Length of Hospitalization. Timepoint: During hospitalization. Method of measurement: Medical Record. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed