metabolic syndrome. Disorders of lipoprotein metabolism and other lipidaemias, Obesity, Other specified diabetes mellitusHypertensive heart disease
Conditions
Interventions
Intervention 1: The intervention group will consume 2 probiotic capsules for 3 months(each white capsule has 250 mg weight , by PROTEXIN). This group will receive a weight loss diet, according to the
Placebo
The intervention group will consume 2 probiotic capsules for 3 months(each white capsule has 250 mg weight , by PROTEXIN). This group will receive a weight loss diet, according to the adjusted ideal b
The placebo group will consume 2 placebo capsules for 3 months which will produce by PROTEXIN similar to probiotic capsules, including maltodextrin. This group will receive a weight loss diet, accordi
Sponsors
National Nutrition and Food Sciences Technology Research Institut
Eligibility
Sex/Gender
All
Age
25 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: To be volunteer to participate in this study; Patients with diagnosis of metabolic syndrome; Aged 25-70; To have a BMI =25kg/m2; Not smoking, pregnant and lactating; Without a diagnosis of thyroid disorders; Not taking medication including: multivitamin-mineral supplements, omega-3, oral contraceptive peel, estrogen, progesterone, corticosteroids or Insulin; Not consuming green tea and fiber powder; Not being a vegetarian or follower of unusual dietary patterns from before the study; Not taking any kind of antibiotic drugs from 1 month before the study. Exclusion criteria: Taking Antibiotic during study; Consuming energy less than 800 or more than 4200 Kcal/day; Consuming less than 2/3 of probiotic supplement; Missing any inclusion criteria during the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Triglycerid. Timepoint: in the begining and after 3 month. Method of measurement: enzymatic method.;Fasting glucose. Timepoint: in the begining and after 3 month. Method of measurement: enzymatic method.;HDL. Timepoint: in the begining and after 3 month. Method of measurement: enzymatic method.;Waist circumference. Timepoint: in the begining, after 1 month, after 2 month and after 3 month. Method of measurement: meter.;Systolic and diastolic pressure. Timepoint: in the begining and after 3 month. Method of measurement: barometer.;Hs-CRP. Timepoint: in the begining and after 3 month. Method of measurement: ELISA.;PYY. Timepoint: in the begining and after 3 month. Method of measurement: ELISA.;GLP-1. Timepoint: in the begining and after 3 month. Method of measurement: ELISA.;Weight. Timepoint: in the begining, after 1 month, after 2 month and after 3 month. Method of measurement: scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Macronutrients intake. Timepoint: in the begining, after 1 month, after 2 months and after 3 months. Method of measurement: food recall questionnaire.;Cholesterol. Timepoint: in the begining and after 3 months. Method of measurement: enzymatic method.;Energy intake. Timepoint: in the begining, after 1 month, after 2 months and after 3 months. Method of measurement: food recall questionnaire.;LDL. Timepoint: in the begining and after 3 months. Method of measurement: Friedwald.;Physical activity. Timepoint: in the begining and after 3 months. Method of measurement: physical activity questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamira Rabiei
Faculty of Nutrition and Food Sciences
Outcome results
None listed