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Evaluating the association of HSV2 infection in HIV progression in HIV positive patients.

Evaluating the association of HSV2 infection in HIV progression in HIV positive patients.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201311094076N12
Enrollment
180
Registered
2014-01-12
Start date
2013-11-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV AIDS. Human immunodeficiency virus [HIV]

Interventions

Intervention 1: Intervention Group: Through this phase, clinical trial with two parallel RCT will be done. In this purpose, HIV-1/HSV-2 co-infected patients will be divided in two groups, 45 particip
Treatment - Drugs
Intervention Group: Through this phase, clinical trial with two parallel RCT will be done. In this purpose, HIV-1/HSV-2 co-infected patients will be divided in two groups, 45 participants in each gr
Control Group: 45 HIV HSV2 positive participants will be recruit in this phase as control group , there is no drug treatment or intervention for this group. After 1 year from the study baseline w

Sponsors

Resaerch Deputy tehran university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criterion: HIV positive patients referred to Iranian Research Center for HIV/AIDS-Imam Khomeini Hospital with CD4 count of 400-900 cells/mm3 and not being under antiviral therapy. Exclusion criteria: CD4 count above 400-900 cells/mm3; co infected with either HBV or HCV; having genital wart.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
CD4 Count. Timepoint: 1 year after intervention and starting for treatment. Method of measurement: Blood Test.;Viral Load. Timepoint: 1 year after intervention and starting for treatment. Method of measurement: Blood Test.

Secondary

MeasureTime frame
HIV progression. Timepoint: 1 year after starting the project. Method of measurement: lab tests and physical exams.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMinoo Mohraz MD

Iranian research Center for HIV AIDS (IRCHA)

ircha@tums.ac.ir ircha.tums.ac.ir+98 21 6658 1583

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026