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Effect of oral clonidine premedication on blood loss in total hip arthroplasty

Comparison of the effect of oral clonidine premedication with placebo on perioperative blood loss in total hip arthroplasty surgery patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20131108015322N5
Enrollment
34
Registered
2021-04-07
Start date
2021-04-09
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative and postoperative blood loss in total hip arthroplasty.

Interventions

Intervention 1: Intervention group: Patients receiving clonidine tablet. Intervention 2: Control group: Patients receiving placebo tablet.

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: ASA class 1 and 2 patients Elective total hip arthroplasty Primary total hip arthroplasty

Exclusion criteria

Exclusion criteria: ASA 3 and 4 patients Patients with BMI greater than 30 Patients with Hb less than 10 Patients with severe liver or kidney diseases Patients taking anticoagulants patients with coagulation disorders Alcoholic patients Revision total hip arthroplasty Patients with previous surgery in the operated area

Design outcomes

Primary

MeasureTime frame
The amount of bleeding during the operation. Timepoint: After intervention during surgery. Method of measurement: Weighing blood gases, amount of blood in the suction bottle, blood in the operative site.

Secondary

MeasureTime frame
Postoperative hemoglobin level. Timepoint: On the first and third day after surgery. Method of measurement: Measured from a blood sample.;Blood transfusion rate. Timepoint: During surgery and in the postoperative period. Method of measurement: Number of transfused units of blood.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShideh dabir

Shahid Beheshti University of Medical Sciences

shdabir@yahoo.com+98 21 2243 2595

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026