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Heart rate changes in strabismus surgery

Comparison of intravenous lidocaine and hyoscine buthylbromide with placebo for oculocardiac reflex frequency in strabismus surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201311069229N4
Enrollment
75
Registered
2014-03-08
Start date
2013-12-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

strabismus. Strabismus, unspecified

Interventions

Intervention 1: Control group: they received 3.5 ml distilled water as placebo before propofol injection. Intervention 2: Intervention group 1 : received intravenous lidocaine 2% (1.5mg/kg ) before pr
Placebo
Treatment - Drugs
Control group: they received 3.5 ml distilled water as placebo before propofol injection
Intervention group 1 : received intravenous lidocaine 2% (1.5mg/kg ) before propofol injection
Intervention group 2 : received intravenous hyoscine buthylbromide (0.2 mg/kg) before propofol injection

Sponsors

Vice Chancellor for Research, Mashhad University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients undergoing strabismus surgery; no history of previous strabismus surgery; both sexes; American Society of Anesthesiology (ASA) I; age between 5-30 years Exclusion criteria: American Society of Anesthesiology (ASA) II and higher; hypertension; coronary artery disease; respiratory disease; diabetes; addiction; use of beta-blocker drugs before surgery; hyoscine and lidocaine allergy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Heart rate. Timepoint: Before induction, after induction, after LMA insertion, start time of surgery, before and after muscle traction. Method of measurement: Intraoperative monitoring.;Dysrhythmia. Timepoint: Before induction, after induction, after LMA insertion, start time of surgery, before and after muscle traction. Method of measurement: Intraoperative monitoring.

Secondary

MeasureTime frame
Blood pressure. Timepoint: Before induction, after induction, after LMA insertion, start time of surgery, before and after muscle traction. Method of measurement: Intraoperative monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehryar Taghavi Gilani

Mashhad University of Medical Sciences

taghavim@mums.ac.ir+98 51 1852 5209

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026