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Assessmen effect of endometrial injury on successful rate of repeated failure of FET

Assessment effect of endometrial injury on rate of successful pregnancy outcomes in infertile patients .

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201311065181N12
Enrollment
120
Registered
2015-10-20
Start date
2012-10-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

femail infertility. Female infertility, unspecified

Interventions

Intervention 1: intervention group: endometrial injury by pipple was done in the 21 th of mensturation cycle &superfact(30 unit=3cc subcutaneous) was started & come back on 3th day of next cycle& es
Treatment - Other
Treatment - Drugs
intervention group: endometrial injury by pipple was done in the 21 th of mensturation cycle &superfact(30 unit=3cc subcutaneous) was started & come back on 3th day of next cycle& estradiol was star
controll group:endometrial injury by pipple was not done&superfact(30 unit=3cc subcutaneous) was started in both & come back on 3th day of next cycle& estradiol was started for both group(6mg daily)&i

Sponsors

Vice Chancellor for Research of Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:age lower than 40 years ,minimum of 4 good fetuses ; minimum of 2 cycle of failure; Endometrial thickness on day of progesterone administration more than 8mm. Exclusion criteria :submucosal myoma larger than 3 centimeter , intramural-subserosal myoma larger than 5 Cm ,endometrioma larger than 3 centimeter ,systemic disease ,Tuberculosis , ,hydrosalpinx+bilateral tubal obstruction,asherman syndrome.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy. Timepoint: 2 weak after trasfer. Method of measurement: Blood sample.;Frozen Embryo Transfer. Timepoint: 2 weak post trasfer. Method of measurement: Transvaginal sonography.

Secondary

MeasureTime frame
Abortion. Timepoint: 2 weaks post transfer. Method of measurement: Transvaginal sonography.;Ectopic pregnancy. Timepoint: 2 weaks post transfer. Method of measurement: trasvaginal sonography&blood sample.;Implantation rate. Timepoint: 2 weaks post transfer. Method of measurement: sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMinou Dashti

Valiasr Reproductive Health Research Center

dashti.minou@gmail.com+98 21 6693 9320

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026