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The efficacy of "Intravenous magnesium sulfate" on bleeding through orthognathic surgery

A clinical trial of using of "Intravenous magnesium sulphate" on delibrate hypotension and bleeding through orthognathic surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201311051674N9
Enrollment
60
Registered
2013-12-09
Start date
2013-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bimaxillary Orthognathic Surgery. 00

Interventions

Intervention 1: Patients in the first group will be received "Magnesium Sulfate" an initial dose of 30 mg / kg body weight intravenously during 15 minutes and then continuously magnesium sulfate 10 mg
Treatment - Drugs
Patients in the first group will be received "Magnesium Sulfate" an initial dose of 30 mg / kg body weight intravenously during 15 minutes and then continuously magnesium sulfate 10 mg / kg / hr via p

Sponsors

Vice-Chancellery of Research and Technology, Shiraz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients with no history of systemic disease and without taking any analgesic medications criteria that were willing to cooperate in this study were enrolled; and Exclusion criteria included known allergy to the study drugs; hepatic and renal dysfunction ; patients with heart block or myocardial damage; morbid obesity (BMI = 35); neuromuscular disease; history of neuropathy; asthma; use of calcium channel blockers and Patients who did not sign the informed consent.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Bleeding during surgery. Timepoint: During operation and postoperative. Method of measurement: CC.

Secondary

MeasureTime frame
Use of blood products. Timepoint: Postoperative. Method of measurement: CC.;Side effects of magnesium sulfate. Timepoint: Intraoperative. Method of measurement: Hemodynamic changes.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Reza Eftekharian

Shiraz University Of Medical

eftekharhr@sums.ac.ir+98 71 1648 3783

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026