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Effect of treatment with oral antibiotics at discharge rates of anal fistula

Evaluation the effect of treatment by oral antibiotics in patients with pre-anal abscess in occurrence of anal fistula within 3 months post operation.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201311049936N7
Enrollment
300
Registered
2014-01-07
Start date
2013-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anal fistula. Anal fistula

Interventions

Intervention 1: Control group: patients with perianal abscess under the standard surgical treatment (incision and drainage) are placed under additional treatment not covered. Intervention 2: Intervent
Treatment - Drugs
Control group: patients with perianal abscess under the standard surgical treatment (incision and drainage) are placed under additional treatment not covered.
Intervention group: patients with perianal abscess under the standard surgical treatment (incision and drainage) is placed at discharge for 7 days, oral antibiotics (ciprofloxacin and metronidazole) i

Sponsors

Vice –Chancellor of Shiraz University of Medical Sciences, Shiraz, Iran
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age older than 16 years and less than 65 years; peri-anal abscess diagnosed by a resident of anorectal surgery; the first patient was admitted because of anal abscess. Exclusion criteria: previous anal surgery; there fistula with abscess; inflammatory disease of the colon; history of pelvic radiation, cellulite; horseshoe abscesses; immunosuppression; diabetes mellitus; heart valve disease; prostheses; obesity; history of hypersensitivity to metronidazole and ciprofloxacin; ischiorectal abscess.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Anal fistula treatment with the use of oral antibiotics after discharge. Timepoint: Two weeks after surgery and initial evaluation of patients during the first three months of using oral antibiotics. Method of measurement: Feeding, The recovery rate, The fistula.

Secondary

MeasureTime frame
Anal fistula treatment without the use of oral antibiotics after discharge. Timepoint: Two weeks after surgery and initial evaluation of patients during the first three months of using oral antibiotics. Method of measurement: Feeding, The recovery rate, The fistula.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Alireza Safarpour

Colorectal Research Center, Shiraz University of Medical Sciences

fsafrpour@yahoo.com+98 71 1230 6972

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026