Renal failure, peritoneal dyalisis. Renal failure
Conditions
Interventions
Intervention 1: Receiving silymarin drug 140mg every 8 hours for 2 month. Intervention 2: in control group we used similar tablet in shape , color to Silymarin drug, which is consisted of starch as pl
Treatment - Drugs
Placebo
Receiving silymarin drug 140mg every 8 hours for 2 month
in control group we used similar tablet in shape , color to Silymarin drug, which is consisted of starch as placebo and they should take each hours for 2 month.
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criterion: patients undergo Peritoneal Dialysis and are on the follow up of nephrologist at Emam reza Clinic between 18-60 years old. Exclusion criteria:patients undergo Peritoneal Dialysis who had peritonitis in recent 2 month; hepatitis; or using other antioxidant, anti pregnancy, levothyroxin drugs and smoking.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glutathione peroxidase antioxidant enzyme in RBC. Timepoint: 2 month (before and after drug). Method of measurement: serlogic blood test.;Antioxidant catalase enzyme. Timepoint: 2 month (before and after drug). Method of measurement: serlogic blood test.;Antioxidant isoprostane enzye F2a. Timepoint: 2 month (before and after drug). Method of measurement: serlogic blood test.;Antioxidant capacity FRAP. Timepoint: 2 month (before and after drug). Method of measurement: serlogic blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSoraya Khajeh Rezae
Shiraz Universitty of Medical Sciences
Outcome results
None listed