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Acne cure rate in patients Hyperandrogenism with two drugs of Decuttane and CYPROTERONE COMPOUND .

Comparison of therapiotic effects of oral Flutamide and Cyproteron compound on female moderate acne

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013110315246N1
Enrollment
30
Registered
2013-12-14
Start date
2012-04-18
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. acne vulgaris

Interventions

Intervention 1: decuttane - isotretinoin 20 mg daily + Azithromycin 250 mg capsules three times a week, erythromycin solution of 4% once a day, oil-free sunscreen and Tcc soap three months. Interventi
Treatment - Drugs
decuttane - isotretinoin 20 mg daily + Azithromycin 250 mg capsules three times a week, erythromycin solution of 4% once a day, oil-free sunscreen and Tcc soap three months
Cyproterone Compound + Azithromycin 250 mg capsules three times a week, erythromycin solution of 4% once a day, oil-free sunscreen and Tcc soap three months

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
14 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 14-45 years old; besides acne hirsutism (Ferriman & Gallwey score greater than or equal to 4) and Ludwing grade one or higher female androgenetic alopecia; absence of contraindications to treatment with tablets decuttane and CYPROTERONE COMPOUND based on questionnaire; not wanting to at least 9 months of pregnancy, or breast-feeding; individual patients signed a consent form Exclusion criteria: drug allergy; pregnancy or lactation; uncooperative patient or patient's consent to continue reading.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Improvement of acne vulgaris lesions. Timepoint: Baseline, three months and one month after the end of treatment. Method of measurement: Indices are calculated based on the Total Acne lesion Count( TLC) and acne severity index (ASI) for each patient.

Secondary

MeasureTime frame
Side effects of drug. Timepoint: Every 6 weeks. Method of measurement: clinical evaluation-liver function test and lipid profile.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Kioumars Jamshidi

Isfahan University of Medical Sciences

kioumars_jamshidi@med.mui.ac.ir; kioumars_jamshidi2009@yahooo.com+98 31 1777 2134

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026